BIOSYSTEMS ENGINEERING RESEARCH GROUP 

 
ZEYNEP ILSEN ONSAN -Publications

Biosystems Engineering Papers 

1. P. Pir, B. Kırdar, A. Hayes, Z. İ. Önsan, K. Ö. Ülgen, S. G. Oliver, Exametabolic and transcriptional response in relation to phenotype and gene copy number in respiration-related deletion mutants of S. cerevisiae, Yeast, 25(9) (2008) 661-672.

2. D. Dikicioglu, P. Pir, Z. İ. Önsan, K. Ö. Ülgen, S. G. Oliver, B. Kırdar, “Integration of metabolic modeling and phenotypic data in the evaluation and improvement of ethanol production using respiratory deficient mutants of Saccharomyces  cerevisiae”, Applied and Environmental Microbiology, 74 (18) (2008)5809-5816.

3. K. Y. Arga, Z. İ. Önsan, B. Kırdar, K.Ö. Ülgen, J. Nielsen, “Understanding signaling in yeast: insights from network analysis” Biotechnology and Bioengineering, 97 (2007) 1246-1258.

4. T. Çakır, B. Kırdar, Z. İ. Önsan, K. Ö. Ülgen, J. Nielsen, “Effect of carbon source perturbations on transcriptional regulation of metabolic fluxes in S. Cerevisiae BMC Systems Biology 1 (2007) Art. No.18, Mar 27, 2007.

5. T. Çakır, K. R. Patil, Z. İ. Önsan, K. Ö. Ülgen, B. Kırdar, J. Nielsen, “Integration of metabolome data with metabolic networks reveals reporter reactions”, Molecular Systems Biology 2006, www.molecularsystemsbiology.com, Article no. 50 (2006) 1-11.

6. P. Pir, B. Kırdar, A. Hayes, Z. İ. Önsan, K. Ö. Ülgen, S. G. Oliver, “Integrative investigation of metabolic and transcriptomic data”, BMC Bioinformatics, 7 (2006) 203 (12 sayfa).

7. P. Pir, K. Ö. Ülgen, A. Hayes, Z. İ. Önsan, B. Kırdar, S. G. Oliver, “Annotation of unknown yeast ORFs by correlation analysis of microarray data and extensive literature searches” Yeast, 23 (2006) 553-571.

8. E. Toksoy Öner, B. Kırdar, Z. İ. Önsan, K. Ö. Ülgen, “Modeling of the induced expression for high-level production of a foreign protein by recombinant E. coli under the control of the T7 phage promoter” Process Biochemistry, 39 (2003) 315-323.

9. M. M. Altıntaş, K. Ö. Ülgen,  B. Kırdar, Z. İ. Önsan, S. G. Oliver, “Optimal substrate feeding policy for fed-batch cultures of the recombinant S. cerevisiae expressing bifunctional fusion protein displaying amylolytic activities”, Enzyme & Microbial Technology, 33(2-3) (2003) 262-269.

10. G. Birol, İ. Birol, B. Kırdar, Z. İ. Önsan, “Investigating the fermentation dynamics structure of recombinant yeast YPB-G” Computers and Chemical Engineering, 27(1) (2003) 45-54.

11. M.M. Altıntaş, K.Ö. Ülgen, B. Kırdar, Z.İ. Önsan, S.G. Oliver, “Improvement of ethanol production from starch by recombinant yeast through manipulation of environmental factors” Enzyme and Microbial Technology, 31 (2002) 640-647.

12. E. Toksoy, Z. İ. Önsan, B. Kırdar, “High level production of TaqI restriction endonuclease by three different expression systems in Escherichia coli cells using T7 phage promoter”, Applied Microbiology and Biotechnology , 59(2-3) (2002) 239-245. 

13. M. M. Altıntaş, B. Kırdar, Z. İ. Önsan, K. Ö. Ülgen, “Cybernetic modeling  of growth and ethanol production in a recombinant S.cerevisiae strain secreting a bifunctional protein Process Biochemistry, 39(12) (2002) 1439-1445.

14. E. Toksoy, Z. İ. Önsan, B. Kırdar, “Expression of a thermostable restriction endonuclease in recombinant E. coli cells and optimization of fermentation conditions” World Journal of Microbiology and Biotechnology, 18 (2002) 23-27.

15. K. Ö. Ülgen, B. Saygılı, Z. İ. Önsan, B. Kırdar, “Bioconversion of starch into ethanol by a recombinant S.cerevisiae strain YPG-AB” Process Biochemistry, 37 (10)(2002) 1157-1168.

16. G. Birol, B. Kırdar, Z. İ. Önsan, “A simple structured model for biomass and extracellular enzyme production with recombinant Saccharomyces cerevisiae YPB-G” Journal of Industrial Microbiology & Biotechnology, 29 (2002) 111-116.

17. M. M. Altıntaş, B. Kırdar, Z. İ. Önsan, K. Ülgen, “Plasmid stability in a recombinant S. cereviaisae strain secreting a bifunctional fusion protein” Journal of Chemical Technology & Biotechnology, 76 (2001) 612-618.

18. E. Toksoy, Z. İ. Önsan, B. Kırdar, “Effect of the co-expression of methyltransferase activity on extracellular production of Taq I restriction endonuclease in recombinant E. coli cells”, Process Biochemistry, 37(5) (2001) 527-534.

19. C. Tamerler,  K. Ülgen, B. Kırdar and Z. İ. Önsan, "A structured model for intracellular EcoRI endonuclease by recombinant E. coli 294", Process Biochemistry, 36 (7) (2001) 621-627.

20. C. Tamerler, Z. İ. Önsan, B. Kırdar, “A comparative study on the recovery of EcoRI endonuclease from two different genetically modified strains of Escherichia coli Turkish Journal of Chemistry  25 (2001) 63-71.

21. G. Birol, Z. İ. Önsan, B. Kırdar, “Studies on fermentation of recombinant yeast cells: stability and kinetics of biomass and protein production” Journal of Chemical Technology & Biotechnology, 75(8) (2000) 729-737.

22. E. Toksoy, P. H. Özdinler, Z. İ. Önsan, B. Kırdar “Extracellular production of TaqI endonuclease in E.coli Biotechnology Techniques, 13-11(1999) 803-808.

23. G. Birol, P. Doruker, B. Kırdar, Z. İ. Önsan, K. Ülgen, “Mathematical description of ethanol fermentation by immobilised Saccharomyces cerevisiae”, Process Biochemistry, 33-7 (1998) 763-771.

24. G. Birol, Z. İ. Önsan, B. Kırdar, S. Oliver,“Ethanol production and fermentation characteristics of recombinant S. cerevisiae strains grown on starch” Enzyme and Microbial Technology, 22 (1998) 672-677.

25. C. Yıldır, Z. İ. Önsan, B. Kırdar, “Optimization of starting time and period of induction and inducer concentration in the production of the restriction enzyme EcoRI from recombinant E.coli 294” Turkish Journal of Chemistry , 22 (1998) 221-226.

26. P. Doruker, Z. İ. Önsan, B. Kırdar, “Ethanol fermentation by growing S.cerevisiae cells immobilized in small Ca-alginate beads” Turkish Journal of Chemistry, 19 (1995) 37-42.

27. K. Özergin, Y. Khoury, Z. İ. Önsan, B. Kırdar, “The effect of immobilization on yeast cell growth and ethanol production” Turkish Journal of Chemistry, 17 (1993) 154-159.

 Catalyst Technology and Reaction Engineering Papers

 28. B. Gülyüz, Ş. Özkara-Aydınoğlu, A. E. Aksoylu, Z. İ. Önsan, “Kinetics of CO oxidation over Pt-CeOx supported on air-oxidized activated carbon” Turkish Journal of Chemistry, in press (2009).

29. M. Karakaya, A. K. Avcı, A. E. Aksoylu, Z. İ. Önsan, “Steady-state and dynamic modeling of  indirect partial oxidation of methane in a wall-coated microchannel” Catalysis Today, 139 (2009) 312-321.  

30. Ö. Tan, E. Maşalacı, Z. İ. Önsan, A. K. Avcı, “Design of a methane processing system producing high purity hydrogen” International Journal of Hydrogen Energy, 33 (2008) 5516-5526.

31. F. Soyal-Baltacıoğlu, A. E. Aksoylu, Z. İ. Önsan, “Steam reforming of ethanol over Pt-Ni catalysts” Catalysis Today, 138 (2008) 183-186.

32. F. Gökaliler, B. S. Çağlayan, Z. İ. Önsan, A. E. Aksoylu, “Hydrogen production by autothermal reforming of LPG for PEM fuel cell applications” International Journal of Hydrogen Energy, 33 (2008) 1383-1391.

33. E. Örücü, F. Gökaliler, A. E. Aksoylu, Z. İ. Önsan, “Ethanol steam reforming for hydrogen production over bimetallic Pt-Ni/d-Al2O3 Catalysis Letters, 120 (1-2) (2008) 198-203.

34. E. Şimşek, Ş. Özkara, A. E. Aksoylu, Z. İ. Önsan, “Preferential CO oxidation over activated carbon supported catalysts in H2-rich streams containing CO2 and H2O” Applied Catalysis A. General, 316 (2007) 169-174.

35. F. Soyal-Baltacıoglu, B. Gülyüz, A. E. Aksoylu, Z. İ. Önsan, “Low temperature CO oxidation kinetics over activated carbon supported Pt-SnOx catalysts” Turkish Journal of Chemistry, 31 (2007) 455-464.

36. Z. İ. Önsan, “Catalytic processes for clean hydrogen production from hydrocarbons” Turkish Journal of Chemistry, 31 (2007) 531-550.

37. G. Uysal, A. N. Akın, Z. İ. Önsan, R. Yıldırım, “Preferential CO oxidation over Pt-SnO2/Al2O3 in hydrogen-rich streams containing CO2 and H2O (CO removal from H2 with PROX)” Catalysis Letters, 111 (3-4) (2006) 173-176.

38. G. Uysal, A. N. Akın, Z. İ. Önsan, R. Yıldırım, “Design of a Pt-Co-Ce/MgO catalyst for preferential CO oxidation” Catalysis Letters, 108(3-4) (2006) 193-196.

39. B. Selen Çağlayan, A. K. Avcı, Z. İ. Önsan, A. E. Aksoylu, “Production of hydrogen over bimetallic Pt-Ni/Al2O3: I. Indirect partial oxidation of propane”, Applied Catalysis A: General, 280 (2005) 181-188. (SCI)

40.  B. Selen Çağlayan, Z. İ. Önsan, A. E. Aksoylu, “Production of hydrogen over bimetallic Pt-Ni/Al2O3: II. Indirect partial oxidation of LPG”, Catalysis Letters, 102(1-2) (2005) 63-67. (SCI)

41. E. Örücü, M. Karakaya, A.K. Avcı, Z.İ. Önsan, “Investigation of ethanol conversion for hydrogen fuel cells using computer simulations”, Journal of Chemical Technology & Biotechnology, 80 (2005) 1103-1110.

42. A. K. Avcı, D. L. Trimm, A. E. Aksoylu, Z. İ. Önsan, “Hydrogen production by steam reforming of n-butane over supported Ni and Pt-Ni Catalysts”, Applied Catalysis A: General, 258 (2004) 235-240.

43. A. K. Avcı, Z. İ. Önsan, D. L. Trimm, “On-board hydrogen generation for fuel cell powered vehicles: the use of methanol and propane” Topics in Catalysis, 22(3-4) (2003) 359-367.

44. A. K. Avcı, D. L. Trimm, A. E. Aksoylu, Z. İ. Önsan, “Ignition characteristics of propane and n-butane over supported Pt, Ni and Pt-Ni catalysts” Catalysis Letters, 88(2003) 17-22.

45. A. K. Avcı, D. L. Trimm, Z. İ. Önsan, “Quantitative investigation of catalytic natural gas conversion for hydrogen fuel cell applications” Chemical Engineering Journal,  90 (2002) 77-87.

46. A. N. Akın, M. Ataman, A. E. Aksoylu, Z. İ. Önsan, “CO2 Fixation by hydrogenation over co-precipitated Co/Al2O3 Reaction Kinetics and Catalysis Letters, 76 (2) (2002) 265-270.

47. D. L. Trimm, Z. İ. Önsan, “On-board fuel conversion for hydrogen fuel cell driven vehicles”, Catalysis Reviews: Science and Engineering, 43 (1-2) (2001) 31-84.

48. A. K. Avcı, Z. İ. Önsan, D. L. Trimm, "On-board fuel conversion for hydrogen fuel cells: Comparison of different fuels by computer simulations", Applied Catalysis A: General,, 216 (2001) 243-256.

49. A. K. Avcı, D. L. Trimm, Z. İ. Önsan “Heterogeneous reactor modeling for simulation of catalytic oxidation and steam reforming of methane”, Chemical Engineering Science, 56 (2) (2001) 641-649.

50.  A. N. Akın, G. Kılaz, A. İ. İşli, Z. İ. Önsan, “Development and characterization of Pt-SnO2/g-Al2O3 catalysts” Chemical Engineering Science, 56(3) (2001) 881-888.

51.  A. N. Akın, Z. İ. Önsan, “Turkish chemical industry and environmentally friendly technologies”, Eurasian Chemico-Technological Journal, 3(4) (2001) 257-266.

52. A. N. Akın, Z. İ. Önsan “CO hydrogenation by K-promoted coprecipitated Co/Al2O3 Reaction Kinetics and Catalysis Letters 70 (2) (2000) 275-280.

53. R. Karaselçuk, A. İ. İşli, A. E. Aksoylu, Z. İ. Önsan., “ CO hydrogenation over bimetallic nickel-vanadium catalysts”,  Applied Catalysis A: General 192 (2000), 263-271.

54. T. Bülbül, T., A. İ. İşli,, A. E. Aksoylu, Z. İ. Önsan, "Investigation of alternative support materials for monometallic and bimetallic catalysts of CO hydrogenation", Studies in Surface Science and Catalysis, 130 (2000) 3723-3728.

55. A.K. Avcı, D.L. Trimm, Z. İ. Önsan, "Simulation of alternative catalyst bed configurations in autothermal hydrogen production", Studies in Surface Science and Catalysis, 130 (2000) 2753-2758.

56. A. N. Akın,  A. E. Aksoylu, Z. İ. Önsan.,“Adsorption and reaction studies on cobalt-alumina catalysts prepared by changing pH coprecipitation”, Reaction Kinetics and Catalysis Letters, 66-2 (1999)393-399.

57. A. E. Aksoylu, A. İ. İşli, Z. İ. Önsan, “Interaction between nickel and molybdenum in bimetallic Ni-Mo/alumina catalysts: III. Effect of impregnation strategy”, Applied Catalysis A: General 183 (1999) 357-364.

58. A. İ. İşli, A. E. Aksoylu, Z. İ. Önsan , “The effect of lanthanum and barium additives on the thermal stabilization of g-alumina”, Turkish Journal of Chemistry , 22 (1998) 253-260.

59. A. E. Aksoylu, Z. Mısırlı, Z. İ. Önsan, “Interaction between nickel and molybdenum in bimetallic Ni-Mo/Alumina catalysts: I. CO2 methanation and SEM-TEM studies”, Applied Catalysis A: General , 168 (1998) 385-397.

60. A. E. Aksoylu, Z. İ. Önsan, “Interaction between nickel and molybdenum in bimetallic Ni-Mo/alumina catalysts: II. CO hydrogenation”, Applied Catalysis A: General , 168 (1998) 399-407.

61. A. E. Aksoylu, Z. İ. Önsan, “Kinetics of CO hydrogenation  over Ni-Mo/alumina catalysts with and without K promotion”, Industrial and Engineering Chemistry Research, 37-6 (1998) 2397-2403.

62. A. N. Akın, Z. İ. Önsan, “The effect of preparation variables on the CO hydrogenation activity of coprecipitated Co-alumina catalysts”, Journal of Chemical Technology & Biotechnology, 69 (1997) 337-344.

63. A. N. Akın, Z. İ. Önsan,“Kinetics of CO hydrogenation over coprecipitated Co-alumina” Journal of Chemical Technology & Biotechnology, 70 (1997) 304-310.

64. A. E. Aksoylu, Z. İ. Önsan,  “Hydrogenation of carbon oxides using coprecipitated and impregnated nickel-alumina catalysts”, Applied Catalysis A: General 164 (1997) 1-11.

65. A. E. Aksoylu, A. N. Akın, S. G. Sunol, Z. İ. Önsan, "The effect of metal loading on the adsorption parameters of carbon dioxide on coprecipitated nickel-alumina catalysts", Turkish Journal of Chemistry, 20 (1996) 88-94.

66. A. E. Aksoylu, A. N. Akın, Z. İ. Önsan, D. L. Trimm, "Structure/activity relationships in coprecipitated nickel/alumina catalysts using CO2 adsorption and methanation”, Applied Catalysis A: General, 145 (1996) 185-193.

67. Z . S. Gönenç, R.Yıldırım, B. Beler-Baykal, Z. İ. Önsan, “Adsorption parameters of some C5-C8 paraffinic hydrocarbons on platinum-alumina by gas chromatographic pulse techniques” Applied Catalysis A: General , 103 (1993) 35-42.

68. F. Kızılçeç, Z. İ. Önsan, F. Borak, “Heat transfer coefficients in finned-coil stirred-tank systems” Canadian Journal of Chemical Engineering, 68(1990) 1057-1060.

69. Z. S. Gönenç, Z. İ. Önsan, “Chromatographic study of the adsorption and reaction of hydrocarbons on a platinum-alumina reforming catalyst” in  Recent Advances in Chemical Engineering (ed. D.N. Saraf, D. Kunzru), Tata-McGraw-Hill, New Delhi (1989) 266-271.

70. A. N. Akın, M. Arıkol,  Z. İ. Önsan, “The effect of temperature and caustic soda concentration on bauxite digestion efficiency” Chimica Acta Turcica, 17-1(1989) 21-29.

71. Z. S. Gönenç, Z. İ. Önsan, “Chromatographic study of hydrogen adsorption on a commercial platinum-alumina reforming catalyst” Turkish Journal of Chemistry, 12-3 (1988) 248-254.

72. F. Özgülşen, F. Borak, Z. İ. Önsan, “Optimal ısı değiştiricilerin tasarımı-1” Mühendis ve Makina Dergisi, 29(1988) 17-21.

73. F. Özgülşen, F. Borak, Z. İ. Önsan, “Optimal ısı değiştiricilerin tasarımı-2” Mühendis ve Makina Dergisi, 29(1988) 26-32.

74. D. Aksan-Sizgek, F. Borak, Z. İ. Önsan, “Heat transfer coefficients in coiled stirred-tank systems” Canadian Journal of Chemical Engineering, 65(1987) 1013-1017.

75. A.Z. Aroğuz, Z.İ. Önsan, “Pyrolysis of solid waste materials” Chimica Acta Turcica, 15-3 (1987) 415-429.

76. H.F. Berk, A.B. Beler, Z. İ. Önsan, R. Kandiyoti, “Kömür kullanım yöntemlerinin hava kirliliğine etkileri- 1. Düşük sıcaklık pirolizi” Çevre Haberleri, 5(1980) 33-37.

77. R. Kandiyoti, Z. İ. Önsan, “Kömür kullanım yöntemlerinin hava kirliliğine etkileri- 2. Gazlaştırma işlemleri” Çevre Haberleri, 8(1980) 15-23.

78. Z. İ. Önsan, A.M. Erten, “Katı atıkların değerlendirilmesinde selülozik maddelerin ısıl bozunması” Çevre Haberleri, 3(1979) 17-22.

79. G. Alptekin, Z. İ. Önsan, R. Kandiyoti, “Hydrodenitrogenation of pyridine over a cobalt molybdate catalyst” Boğaziçi University Journal, 7(1979) 1-22.

80. İ. Z. Önsan, D.L. Trimm, “The ammoxidation of propene and isobutene over an Sn-V-P oxides catalyst”, Journal of Catalysis, 38(1975) 257-263.