The initiative towards cleaner and safer technologies has made it imperative to consider biotechnology as an indispensable option in reaching that goal. Enabling cost-effective large-scale production of valuable commodities through the use of cell factories as well as understanding of the molecular mechanisms leading to complex human genetic disorders such as cardiovascular disorders, cancer, Alzheimer’s disease requires the application of a system based and targeted approach as well as educated manipulations of biological systems.
Systems biology aims to integrate the biological information obtained at different levels using high-throughput technologies to understand the complexity of life and develop in silico models to simulate the processes of life. An organism is considered to be an integrated and interacting network of genes, proteins, metabolites and biochemical reactions which give rise to life. Biological information is processed in complex networks and it operates at multiple hierarchical levels of organization.
Biosystems Engineering Research Group aims to understand an integrated view of the molecular basis of life using Systems Biology approaches and to design rational strategies for the construction of industrially important microorganisms to develop new products and/or improved processes using metabolic and genetic engineering techniques.